Fasting, which leads to deprivation of food produces certain protein that adjusts the metabolism in the liver, which eventually results in protection from fatty liver disease.
A reduced intake of calories facilitated by the voluntary act of fasting can help to whip the metabolism back into shape. During fasting, the stress molecule reduces the absorption of fatty acids in the liver and improves sugar metabolism.
GADD45 beta — protein, whose name stands for ‘Growth Arrest and DNA Damage-inducible’ – controls the absorption of fatty acids in the liver, during the time of fasting. The stress on the lever cells caused by scheduled fasting stimulates GADD45 beta production, which then adjusts the metabolism to the low food intake.
The human body with a low GADD45 beta level was accompanied by increased fat accumulation in the liver and an elevated blood sugar level.
The scientists are working for the translating the positive effects of food deprivation for treatment.